Myasthenia Gravis: A Manual for the Health Care Provider (PDF)
In 2008, MGFA published the first comprehensive manual on myasthenia gravis specifically for health care professionals. This handbook is written as an aid for health care personnel who are involved in the care and management of MG patients. The manual is divided into sections for ease in assisting the health care professionals in their evaluation, diagnosis and management of MG patients.
Sections address issues related to:
• Physician Information
• Emergency Care
• Psychosocial: From Diagnosis to Lifetime Management
• Physical Therapy
• Occupational Therapy
• Speech Pathology and Swallowing
• Dental Care
• Guidelines for the Pharmacist
Printed copies are shipped at a cost of $12.00 plus shipping and handling each.
CD copies are shipped at a cost of $3.00 plus shipping and handling each.
Call the national office at (800) 541-5454 or order online here.
Medications and Myasthenia Gravis (A Reference for Health Care Professionals) (PDF)
QOL and ADL
The MGQOL 15: It is a survey designed to assess aspects of life related to myasthenia gravis. There is appropriate correlation between the 15 item MG-QOL 15 and other MG-specific scales (MGC, MG-ADL, and MG-MMT). The MG-QOL 15 has construct validity in the clinical practice setting and represents an efficient and valuable to for assessing quality of life for patient with MG. However the magnitude of change required to indicate improvement or worsening is variable and depends on MG severity. The MG-QOL 15 can be completed by the patient or administered by the physician or trained clinic personnel or study coordinator.
Download the MGQOL15 here.
References: Burns, TM, Grouse CK, Conway MR, Sanders, DB, and mg composite and mg qol-15 study group. Construct and concurrent validation of the MG-QOL 15 in the practice setting. Muscle Nerve. 2010;41(2):219-226.
Burns, TM, Grouse CK, Wolfe, GI, Conway MR, Sanders, DB; mg composite and mg qol-15 study group. The MG-QOL 15 for following health-related quality of life of patients with myasthenia gravis. Muscle Nerve 2011;43 (1):14-18
MG Activities of Daily Living (MG-ADL): The MG-ADL profile provides a rapid assessment of MG symptom severity; it has been validated and shown to correlate with the QMG score. The MG-ADL correlates strongly with newer, validated MG outcome measures (MGC and MGQOL15). A 2 point improvement in the MG-ADL indicates clinical improvement. The MG-ADL is useful as a research tool and in routine clinical management. The MG-ADL score can be administered by the physician or trained clinic personnel or study coordinator.
Download the MG-ADL here.
References: Wolfe, GI, Herbelin L, Nations, SP, Foster, B, Bryan WW, Barohn RJ. Myasthenia gravis activities of daily living profile. Neurology. 1999;52:1487-1489
Muppidi S, Wolfe, GI, Conaway M, Burns, TM; MG composite and MG-QOL15 study group. MG ADL: still a relevant outcome measure. Muscle Nerve,2011;44(5):727-731.
Clinical Research Standards (PDF)
In 2000, a task force of the MGFA Medical/Scientific Advisory Board published a paper proposing classification systems for the severity of MG and definitions of response to therapy in MG to achieve uniformity in recording and reporting clinical trials and outcomes research.
For an updated recommendation for myasthenia gravis clinical trials, please see the following document.
The Neurologist, January 2002: Myasthenia Gravis
Michael W. Nicolle, M.D. FRCPC D. Phil.
A summary of diagnosis and treatment methods
eMedicine is the most authoritative and accessible point of care medical reference available to physicians and other health care professionals on the Internet. The evidence-based content, updated regularly by more than 8,000 attributed physician or health care provider authors and editors, provides the latest practice guidelines in 38 clinical areas.
from the National Library of Medicine of the National Institutes of Health
MedlinePlus is the National Institutes of Health's Web site for patients and their families and friends. Produced by the National Library of Medicine, it provides relevant information about diseases, conditions, and wellness issues in language you can understand.
The Quantitative Myasthenia Gravis (QMG) Test: The Manual (PDF)
This manual and the accompanying DVD have been designed to instruct clinical evaluators and physicians on how to perform the Quantitative Myasthenia Gravis (QMG) test. For the accompanying videotape contact the national office.